Joseph Priestley discovers oxygen; later, Antoine Lavoisier clarifies the nature of elements. Priestley produces oxygen in experiments and describes its role in combustion and respiration. Then, by dissolving fixed air in water, he invents carbonated water.
John Dalton provides a way of linking invisible atoms to measurable quantities like the volume of a gas or mass of a mineral. His atomic theory states that elements consist of tiny particles called atoms. Thus, a pure element consists of identical atoms, all with the same mass, and compounds consist of atoms of different elements combined together.
Italian chemist Amedeo Avogadro finds that the atoms in elements combine to form molecules. Avogadro proposes that equal volumes of gases under equal conditions of temperature and pressure contain equal numbers of molecules.
Friedrich Woehler accidentally synthesizes urea from inorganic materials, proving that substances made by living things can be reproduced with nonliving substances.
Dmitry Mendeleyev realizes that if all of the 63 known elements are arranged in order of increasing atomic weight, their properties are repeated according to certain periodic cycles. He formulates the periodic table of the elements and predicts the existence of elements that have not yet been discovered. Three of those elements are found during his lifetime: gallium, scandium and germanium.
Humphry Davy finds that electricity transforms chemicals. He uses an electric pile (an early battery) to separate salts by a process now known as electrolysis. With many batteries he is able to separate elemental potassium and sodium in calcium, strontium, barium and magnesium.
J.J. Thomson discovers that the negatively charged particles emitted by cathode ray tubes are smaller than atoms and part of all atoms. He calls these particles, now known as electrons, "corpuscles."
Niels Bohr publishes his model of atomic structure in which electrons travel in specific orbits around the nucleus, and the chemical properties of an element are largely determined by the number of electrons in its atoms' outer orbits. This paves the way to an understanding of how electrons are involved in chemical bonding.
Marie and Pierre Curie discover and isolate radioactive materials. After chemically extracting uranium from uranium ore, Marie notes the residual material is more "active" than the pure uranium. She concludes that the ore contains, in addition to uranium, new elements that are also radioactive. This leads to the discovery of the elements polonium and radium.
Robert Curl, Harold Kroto and Rick Smalley discover an entirely new class of carbon compound with a cage-like structure. A fullerene is any molecule composed entirely of carbon, in the form of a hollow sphere, ellipsoid, or tube.